Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. ...

he Western Cambodia region is infamous for its malaria parasites. Twice already in the 1950s and the 1960s they have developed resistance to key drugs, and the underlying mutations spread inevitably around the world, forcing ...

Artemisinin-based combination therapy (ACT) is currently adopted drug regimen the management of both uncomplicated and severe falciparum malaria, targeting asexual blood-stage Plasmodium falciparum parasites. However, the ...

Abstract Background: Malaria interventions particularly malaria vector control has gained popularity within the last twenty years. Sumitomo Chemical Company has developed a larvicide, Sumilarv 0.5G, based on the insect ...