Besifloxacin hydrochloride (BSF) is a fourth-generation fluoroquinolone-type ophthalmic antibiotic for the treatment of bacterial conjunctivitis. However, its low water solubility limits its therapeutic efficacy. The ...

Cardiovascular disease is a major cause of death globally. This has led to significant efforts to develop new anti‐thrombotic therapies or re‐purpose existing drugs to treat cardiovascular diseases. Due to difficulties ...

he Western Cambodia region is infamous for its malaria parasites. Twice already in the 1950s and the 1960s they have developed resistance to key drugs, and the underlying mutations spread inevitably around the world, forcing ...

Artemisinin-based combination therapy (ACT) is currently adopted drug regimen the management of both uncomplicated and severe falciparum malaria, targeting asexual blood-stage Plasmodium falciparum parasites. However, the ...

Abstract Background: Malaria interventions particularly malaria vector control has gained popularity within the last twenty years. Sumitomo Chemical Company has developed a larvicide, Sumilarv 0.5G, based on the insect ...

Microbial infections are a major public health concern. We investigated prevalence of E. coli pathotypes and Shigella serogroups and their antimicrobial profiles among diarrheic children in Nairobi city, Kenya. Although ...

Youth-development funds play a great role in availing resources to the youth so that they can start their own enterprises with an aim of being self-reliant. The government of Kenya through the youth enterprise fund finances ...

An understanding of the immunogenetic basis of naturally acquired immunity to Plasmodium falciparum infection would aid in the designing of a rationally based malaria vaccine. Variants within the Fc gamma receptors (FcγRs) ...